SINGLE CELL DUAL-OMIC ATLAS OF THE HUMAN DEVELOPING RETINA

Single cell dual-omic atlas of the human developing retina

Abstract The development of the retina is under tight temporal and spatial control.To gain insights into the molecular basis of this process, we generate a single-nuclei dual-omic atlas of the human developing retina with approximately 220,000 nuclei from 14 human embryos and fetuses aged between 8 and 23-weeks post-conception with matched macular

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Kilohertz waveforms optimized to produce closed-state Na+ channel inactivation eliminate onset response in nerve conduction block.

The delivery of kilohertz frequency alternating current (KHFAC) generates rapid, controlled, and reversible conduction block in motor, sensory, and autonomic nerves, but causes transient ngetikin.com activation of action potentials at the onset of the blocking current.We implemented a novel engineering optimization approach to design blocking wavef

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